As soon as you begin to familiarize yourself with the world of cannabis, you begin to hear about cannabinoids such as THC and CBD. And while the most likely thing is that if you came to this article, you already know what we are talking about, let's briefly recap. Cannabinoids, specifically THC, are an active component of cannabis that, when smoked, are mostly responsible for generating the effects that have created so much controversy over the years. At the same time, the series of effects that THC causes can be therapeutic and of great help for some users. However, delta 9 is only the tip of the iceberg. This cannabinoid has some variants that can fulfill different functions in the body depending on how you consume it, act in different ways, and generate other effects. In this article, we will talk a little about 11-Hydroxy-THC, or Delta 11 THC, a variant of THC that is not so well known to most cannabis users. You may have heard that THC-rich cannabis-infused edibles hit harder than just smoking a joint. Well, 11-Hydroxy-THC has a lot to do with this. But how are 11-Hydroxy-THC and Delta 9 THC related? What happens to THC once it enters our body? Why do edibles hit harder than smoking cannabis? In this article, you will find the answers to these questions. We will delve a little deeper into how our body metabolizes THC and what happens to this cannabinoid as our body digests it. Delta 9, 10 & HHC! The gang's all here at Botany Farms.
What is 11-hydroxy-THC?11-Hydroxy-THC, or Delta 11 THC is a metabolite that occurs in our body after we ingest THC. Our gastrointestinal system, including the liver, breaks down the famous Delta-9 during the digestion process, thus forming 11-Hydroxy, also known as 11-OH-THC. We must highlight that 11-Hydroxy-THC does not occur naturally in the cannabis plant, nor does it come from smoking cannabis. 11-Hydroxy-THC only happens when we ingest cannabis and only if it is adequately decarboxylated. The way our bodies absorb and assimilate 11-Hydroxy-THC is what gives cannabis-infused edibles their distinctive high and makes them "kick harder."
How Does 11-Hydroxy-THC Work?The transformation of Delta-9 to 11-Hydroxy-THC begins in the stomach but mostly takes place in the liver. There, the organ transfers 11-OH-THC to our bloodstream through which it can reach our brain to generate its effects. Then, 11-Hydroxy-THC, like the rest of the cannabinoids, interacts with our endocannabinoid system. The difference is that the work our body does to break the Delta-9 THC increases the bioavailability of this cannabinoid in our system. Regardless of how you consume Delta 9 THC, your liver will convert it to 11-OH-THC. However, if you smoke cannabis, the Delta 9-THC content in it will enter your body through your lungs, and as only a little circulatory blood enters the liver at a time, the conversion of Delta 9 THC to 11-OH-THC is much slower.
Benefits Of 11-Hydroxy-THCAlthough 11-Hydroxy-THC (Delta 11 THC) and Delta 9 are closely related, the human body assimilates and metabolizes them differently. Also, the effects of 11-Hydroxy-THC, compared to delta 9, can vary a bit. Some studies suggest that 11-OH-THC is more psychoactive than Delta 9 THC and can cross the blood-brain barrier significantly faster. In addition, 11-OH-THC is the compound most responsible for the "munchies" because it is an appetite enhancer. In fact, the lag between Delta 9 THC consumption and munchies is only due to the time it takes for the liver to metabolize Delta 9 into 11-OH-THC. Other than this, the effects and benefits of 11 hydroxy are pretty similar to the ones caused by Delta 9. As we said, no matter how you consume Delta 9, eventually, the body digests it into 11-OH-THC. Among other benefits of 11-Hydroxy-THC, we have that this compound can help with:
- Lack Of Appetite
- Muscle Spasms
11-Hydroxy-THC DosageThe exact ideal dosage of 11-Hydroxy-THC is quite tricky, if not impossible, to determine. However, when you make cannabis edibles, they initially contain Delta-9 THC. So, we can link the dosage of 11-Hydroxy-THC to the consumption of cannabis edibles because the body eventually metabolizes Delta 9 THC content into 11-Hydroxy. Each person has a unique internal physiology, and therefore, each medication experience can vary greatly depending on the person, especially herbal medications. With cannabis, several factors can make a difference, such as digestive factors, tolerance or history of previous use, and the sensitivity and functionality of each person’s endocannabinoid system. For example, some people are susceptible to cannabis and may not need doses greater than 1 to 5 mg of cannabis when ingested to achieve its full potential. So if you eat cannabis edibles rich in Delta 9 THC, you already know that your body will transform it into 11-Hydroxy-THC. Considering this, we will describe a little the effects it can generate in relation to the amounts ingested. Thus, we find that:
- 1 to 2.5mg THC: Effects include increased focus and creativity. The relief of mild symptoms of stress, anxiety, and pain. This dosage is ideal for patients looking to microdose.
- 2.5 to 15mg of THC: You may experience an inevitable deterioration in coordination and perception and a certain feeling of euphoria. At the same time, get relief from stronger symptoms of anxiety and pain. In addition, this dose improves the quality of sleep.
- 15 to 30mg of THC: May cause impaired perception and coordination. Unaccustomed patients may experience some unwanted effects. This dose is ideal for previously medicated patients with a history of higher tolerance and for patients seeking help to treat insomnia.
- 30 to 50mg of THC: For patients with a significant tolerance to THC or with low absorption of cannabinoids. Coordination and perception will definitely be affected, and this type of dose can generate an intense euphoria in unaccustomed users.
- 50 to 100mg THC: This 11-Hydroxy-THC dosage is only for experienced users with a high tolerance to THC. It is ideal for cancer patients, inflammatory disorders, and conditions that need high doses of THC. However, this amount of 11 hydroxy has a high probability of impairing perception and coordination. Moreover, this compound can generate some negative effects such as increased heart rate, nausea, and pain.