Best Cannabinoid for Inflammation

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Table Of Contents
Inflammation is an issue that affects millions across the U.S. - from arthritis to cardiovascular issues to inflammatory bowel disease. While the pharmaceutical companies have got all of their ducks in a row, many people are also exploring alternative and more natural options to ease their aches in pains. The cannabis industry is growing exponentially, creating more and more personalized and specialized cannabis experiences. Playing around with cannabinoids is one of the big ways the weed world is doing this, and studies are giving us hopeful results. Let’s explore how to say goodbye to inflammation and get a little more educated along the way.

Key Takeaways

  • Some cannabinoids, like CBD, CBG, THC, and CBN, may have potential anti-inflammatory effects.
  • There are over a hundred different cannabinoids in cannabis.
  • Different cannabinoid products are becoming increasingly popular.
  • Hemp-derived cannabinoid products are federally legal due to the 2018 Farm Bill.

What are Cannabinoids?

While you’ve definitely heard about cannabinoids, do you know what they are? To keep it simple, cannabinoids are natural compounds that you find in the cannabis plant. Every cannabinoid interacts differently with your endocannabinoid system and can have different effects and benefits.

Are Cannabinoids Anti-Inflammatory?

There are still some things we don’t know about cannabinoids, but we’re learning every day. Research has suggested that some cannabinoids can have anti-inflammatory effects when making contact with the endocannabinoid system, like CBD, CBG, and THC.

How Do Cannabinoids Help with Inflammation?

If all the studies are right, some cannabinoids have the potential to be great anti-inflammatory agents. So how exactly does it all work? It starts off with the interaction between the cannabinoids and the endocannabinoid system: the effects range from inhibiting pro-inflammatory molecules and the modulation of immune cell activity to the inhibition of inflammatory enzymes and antioxidative properties.

Best Cannabinoids for Inflammation

Because cannabinoids are experiencing a boom in the cannabis world, it’s important for you to have the information and tools to know exactly what you’re getting into. Let’s get into a quick little masterclass on some of the most popular of over a hundred cannabinoids.

Tetrahydrocannabinol (THC)

Tetrahydrocannabinol, or Delta 9 Tetrahydrocannabinol, better known as THC, is arguably the most well-known cannabinoid and the one famous for getting people high as a kite. While some research has suggested that THC may help with inflammation, it's best blended with CBD for a more specialized anti-inflammatory experience.

Cannabidiol (CBD)

Another popular cannabinoid is cannabidiol, more commonly known as CBD. THC’s kid-friendly cousin isn’t psychoactive but has been extensively researched due to its many potential therapeutic benefits. Within these benefits, CBD has also shown promise in being an anti-inflammatory agent.

Cannabinol (CBN)

Cannabinol, or CBN, is next in line. This minor cannabinoid has potential anti-inflammatory benefits, although more studies need to be done. Still, many people turn to CBN and other cannabinoids for conditions like arthritis, neuroinflammation, and skin inflammation.

Cannabigerol (CBG)

Cannabigerol, or CBG, has given us many hopeful preliminary results in studies about being an anti-inflammatory agent. It seems to inhibit pro-inflammatory molecules and modulate immune responses when it interacts with the endocannabinoid system.

Hexahydrocannabinol (HHC)

Hexahydrocannabinol, or HHC, isn’t a well-known cannabinoid, although it’s chemically similar to THC. Just like other cannabinoids, it interacts with CB1 AND CB2 receptors and may play a role in regulating bodily functions, although results aren’t conclusive.

Tetrahydrocannabivarin (THCV)

Tetrahydrocannabivarin is quite a word, so it’s probably best to stick to the THCV nickname. While it doesn’t seem to be an anti-inflammatory agent, it seems to help in other areas like energy stimulation and neuroprotective properties.


Delta 8 Tetrahydrocannabinol, often known as Delta 8, is very similar in structure to Delta 9 THC, which is usually just known as THC. It’s a bit less psychoactive but can have similar effects and possible anti-inflammatory and analgesic effects.


Another chemical cousin of THC is Delta 10 Tetrahydrocannabinol. It’s naturally occurring in small amounts in cannabis plants and has mild psychoactive effects. While it might have anti-inflammatory and analgesic effects, it’s yet to be definitively studied.

THC vs CBD vs CBN vs CBG - How Do They Compare?

Cannabis can have all cannabinoids - THC, CBD, CBN, CBG, and many more. Although some are similar, there’s a reason why we differentiate them. So how are they different from each other? THC is the most well-known psychoactive cannabis compound. If you’ve ever gotten high off of a joint in a parking lot somewhere, you’re probably familiar with THC. It has been widely studied and has potential analgesic, anti-inflammatory, and antiemetic benefits along with strong psychoactive effects. CBD is not psychoactive, which means it won’t get you high. However, CBD is the cannabinoid most used for therapeutic reasons, with many a study talking about the potential anti-inflammatory, analgesic, anxiolytic, neuroprotective, and other effects. CBD is considered generally safe and is the most popular cannabis consumed. CBN is a minor cannabinoid that hasn’t made much of a splash, but it’s recently been growing in popularity. This cannabinoid might not have strong psychoactive effects, but it is known for its sedative benefits that help people relax and get a full night’s sleep. CBG is another minor cannabinoid that isn’t completely famous yet, although it’s slowly changing. It’s thought to have anti-inflammatory, antibacterial, and neuroprotective effects that could potentially help people with various health issues.

Delta 8 vs Delta 9 vs Delta 10 - How Do They Compare?

Delta 8, Delta 9, and Delta 10 could be siblings, but even siblings can be wildly different. Although they share a similar chemical structure, they differ in effects. Delta 8 is similar to Delta 9 but is often found in much lower concentrations. It’s known as being less psychoactive than Delta 9 but still can get you high, although you might feel a little more clear-headed than usual. Delta 9 is the most well-known cannabinoid that’s usually just called THC. It causes the high that cannabis is known for and can make you feel euphoric, and relaxed, and alter your entire perception. It may potentially have health-related benefits. Delta 10 is not as well known as Delta 9 or Delta 8, but it’s around and here to stay. Much more research is needed to understand exactly what it does and why, but it’s thought to be less intense than Delta 9 while sharing some effects and benefits.

Does the Delivery Method Make a Difference?

The way you ingest or use cannabinoid products can make a huge difference in how the effects affect your body. For example, it’s widely known that edibles like gummies and brownies may take longer to kick in but can offer very intense effects. Smoking or vaping lets you feel the effects immediately, but they won’t last as long. Topical application is localized to the area and best for specific aches and pains. These are some of the most popular ways to use cannabis products, and at the end of the day, the best option for you depends on what you want to get out of the experience.

So, Which Cannabinoid is Best for Inflammation?

There are many cannabinoids we need to learn more about so that we can determine if they’re helpful for inflammation issues, but we do know enough to give you some ideas. Based on initial research, cannabinoids like CBD, CBG, THC, and CBN have been shown to have potential anti-inflammatory effects, although it’s always best to talk to a medical professional you trust before going wild.

Final Thoughts

We can’t deny the fact that cannabinoid products are gaining attention, so it’s important to understand what they are and what they do. If you’re one of millions suffering from inflammation-related issues and looking for alternatives because most things don’t work for you, looking into cannabinoids is a good place to start. Some cannabinoids have shown promise in being anti-inflammatory agents, and although we’re still waiting for more results to crawl in, it’s also exciting to be a part of a cannabis renaissance that’s making cannabis products more accessible for everyone.

Where to Find a Wide Selection of Cannabinoids Online

It can be tough to find cannabinoid products that you know you can trust, but the beauty of the modern world is how easy it is to get high-quality cannabinoids sent right to your doorstep. If all of this has piqued your cannabis curiosity, Botany Farms has got your back. We’re super committed to quality and transparency, and think everyone should have access to the best the cannabis world has to offer. If you want to try CBD, you can’t miss the Live Resin CBD Tincture. If the earthy, citrusy, and sour apple notes don’t convince you, 50mg of CBD and 3mg of THC have to. This is one of the strongest full-spectrum CBD products out there, so take it easy and enjoy the peaceful effects. We also carry totally federally legal Delta 9, believe it or not. If you want to take a walk on the wild side, consider popping a Delta 9 Microdose Gummies. While they only have 5mg of Delta 9 and another 5mg of CBD, the effects are smooth, relaxing, and energizing, and make for an easy ride through and through.

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