What is Isopulegol?

Lemongrass full of Isopulegol

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Disclaimer: The information provided here is intended solely for informational and entertainment purposes. It should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen. Never disregard professional medical advice or delay in seeking it because of something you have read here. .

Isopulegol, meanwhile, belongs to a family of compounds known as terpenes, the organic chemicals that account for the intoxicating and extremely diverse array of aromas and tastes found in cannabis and many other plants. Plants produce terpenes to lure pollinators and ward off predators, but humans are finding more uses for them – including helping you enjoy your cannabis more completely.

Terpenes are a main ingredient in the aromatics that perfume your household goods (soaps, for example), as well as the majority of insect repellents that keep your skin rash- and bite-free. They also keep your pets from suffering the indignity (and risks) of parasitic infestation and the diseases that accompany them.

Key Takeaways

  • Nature and Uses: Isopulegol is a terpene with a minty scent, used extensively in the fragrance and flavor industries. It serves as a precursor to menthol, which is found in various therapeutic and personal care products.

  • Biological Activity: The article highlights several biological properties of isopulegol, including anti-inflammatory, gastroprotective, antiviral, anxiolytic, and anticonvulsive effects. These properties make isopulegol a compound of interest in medical research and potential therapies.

  • Research and Studies: The article cites multiple studies that have investigated the effects of isopulegol, including its anti-inflammatory properties and efficacy in treating conditions like epilepsy through its anticonvulsant effects.

Isopulegol Terpene

Isopulegol is never the star of a cannabis strain: it is a supporting terpene that, with a gentle minty scent, contributes to the complexity and appeal of the plants that carry it. To get a sense of what isopulegol is like, think of the eucalyptusy mint whiff of anise hyssop, lemon verbena, lemongrass, lemon balm or geranium. It is also found in parsley and mint.

What does Isopulegol do?

Isopulegol is at work when you use menthol. Nations with giant industries such as India, China, Germany and the US make menthol from frozen peppermint oil – an essential oil that doubles as a good treatment for headaches. This is one of the many therapeutic benefits of this terpene.

Isopulegol Effects

Beyond its fragrance, however, isopulegol is one of many compounds in cannabis that occurs together with other metabolites at the right time and place to exert a particular synergistic effect – the effect observed by the consumer that makes the experience better than if only the constituent parts, like cannabinoids or terpenes, acted by themselves.

Isopulegol Uses

Isopulegol is a cooling agent that makes it a star ingredient in everything from cosmetics to soaps and other personal care products Indeed, the cooling properties of the aforementioned isopulegol would be a helpful hint that it is, in fact, a chemical precursor to menthol, the common ingredient in the essential peppermint oil reported by many as an effective headache remedy, and indeed any number of over-the-counter medicinal preparations.

Isopulegol Benefits

Anti-inflammatory: A 2013 study published in the journal Advances in Pharmacological Sciences found that Melissa officinalis oil, where Isopulegol is a significant component, has a potent anti-inflammatory incidence. The researchers used oil containing 22% isopulegol and dramatically reduced swelling in animals, suggesting that it could be a valuable tool for fighting inflammation.

Gastroprotective: A 2009 German study on gastric ulcer models in mice assessed that Isopulegol had remarkable protective abilities in your stomach. Various researchers concluded that Isopulegol might also possess antioxidant properties, which is a shared property among terpenes.

Antiviral: An English in vitro study published in 2018 tested Isopulegol for its antiviral properties. The researchers found that this terpene could be highly effective during the early stages of the H1N1 and H1N2 strains of the influenza virus, demonstrating its antiviral incidence in living organisms.

Anxiolytic: Brazilian researchers conducted a study published in 2007 that indicated that Isopulegol produces anti-anxiety effects similar to specialized medication in rodents. Simultaneously, it made some depression behaviors worse. It is still not sure how isopulegol contributes to the anti-anxiety effect of cannabis in people.

Anticonvulsive: Due to its antioxidant properties, isopulegol seems to be a good anticonvulsant in animals. Like several other cannabinoids and terpenes, Isopulegol has demonstrable anticonvulsant effects. The combined actions of the organic compounds present in cannabis may be helpful to fight epilepsy.

Isopulegol Smell

Isopulegol feels like taking a couple of Menthols and having the cooling sensation of the mint on your palate. Similarly, you can compare it to taking a good breath on a eucalyptus leaf, which gives you a tingly feeling in your nose.

Isopulegol Strains

Kosher Tangie

Kosher is the offspring of two tremendous strains that provide this indica-dominant hybrid with top-shelf genetics. Kosher Kush contributes with its musky pine aroma while enjoying Tangie’s sweet tangerine notes and a complex terpene profile that lifts your spirit.


OG Kush and Sour Diesel gave birth to the great Headband Marijuana strain that indulges users with its creamy smoke between the citrus and lemon notes and diesel bitter power. The effects of Headband creep up slowly, but they are potent to kill pain and relieve stress.

OG Kush

OG Kush is a premium strain that has earned its crown since the 1990’s scene. The unique terpene profile of OG Kush results from crossing Chemdawg, Lemon Thai, and Hindu Kush, resulting in a special strain in terms of spicy and skunky aroma and relaxing effects.

What is Isopulegol: Frequently Ask Questions

What Is The Use Of Isopulegol?

Isopulegol (also known as Menthone, menthone or pulegol) is a naturally occurring monocyclic monoterpenoid, used in many industries as a flavour and fragrance (minty). Isopulegol is a synthetic intermediate in the synthesis of menthol, used extensively in drugs, cosmetics and foods for its cooling and soothing effects. The application of isopulegol is being developed and applied to therapies because of its anti-inflammatory and gastroprotective properties.

What Strains Have Isopulegol In Them?

Isopulegol is found in many strains of cannabis, contributing to the plant’s terpene or aromatic profile and effects. Strains high in terpenes, especially those with a minty or citrus aroma, are more likely to have higher levels of isopulegol. Some strains that likely have higher levels of the terpene include Lemon Haze, OG Kush and Jack Herer. Of course, lab results for any specific individual batch are the only way to determine a strain’s actual profile.

What Is The Biological Activity Of Isopulegol?

Isopulegol has other interesting biological properties, such as its anti-inflammatory, antioxidant and gastroprotective effects. Studies have shown that it can help to alleviate inflammation, which could be of some help in treating diseases such as arthritis or bronchitis. Its antioxidant properties can protect cells from oxidative stress and, perhaps most excitingly, isopulegol protects the gastrointestinal tract from ulcers and damage, due to its capacity to modulate gastric acid secretion.

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Note: This article is provided by Botany Farms for informational purposes only and does not constitute medical advice. The content is intended to offer insights into the practice of dabbing and the use of cannabis concentrates, reflecting current knowledge and research within these areas. It is not aimed at diagnosing, treating, curing, or preventing any diseases or health conditions. As the legal status of cannabis varies across different regions, it is the responsibility of the reader to be informed about their local laws regarding cannabis use. Botany Farms advises all readers to consult with a healthcare professional before making any decisions about cannabis consumption to understand fully the potential risks and benefits. Botany Farms and the authors of this content disclaim all liability for any adverse effects that may arise from the use of information provided in this article.

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